Every now and again a treatment comes along which is a real game changer, and seems too good to be true. However with the use of the latest treatment in managing chronic joint and arthritis pain we have seen such wonderful results that we have been blown away.
Watch Siva and Emma’s Stories Story
Beransa (Betinvetmab) for dogs is innovative new therapy called a Therapeutic Monoclonal Antibody (MoAb), which helps alleviate arthritis pain. It is a Biotherapy that works by neutralizing a protein called NGF (Nerve Growth Factor). High levels of NGF have been detected in Osteoarthritic joints. When a joint is arthritic and damaged, increased amounts of NGF is released. These high levels trigger a cascade of changes which ultimately result in more inflammation, pain and joint degradation. Beransa is similar in many ways to naturally produced antibodies and is metabolized and eliminated via normal protein degradation pathways with minimal involvement of the liver or kidneys.
Effects of increased NGF levels on joints
- Increased Sensitization of nerves receptors ( Nociceptors) and pain perception
- Increasing inflammation within and around the joint that leads to more damage by inflammatory mediators
- Speeds up the progression of joint degeneration and osteoarthritis.
The end result is more pain and increased joint damage.
Beransa is able to block the action of NGF, which has many benefits including
- Reduced nerve sensitivity
- Regression of additional nociceptors ( pain receptors)
- Reduce inflammation
- Reduced joint pain
- Slowing down the progression of further joint damage
The positive results have far exceeded our expectations, and we thrilled to see so many pets happier and enjoying the things they used to again.
With over 25million doses distributed world wide it is clear that the positive impact we have seen has been echoed all around the world.
What we have noted after starting patients on Beransa;
- Reduced pain on examination
- Improved mobility, for example able to sit and stand easier.
- Reduced lameness,
- Reduced stiffness
- Generally happier and more playful
What our clients have told us
“They have been playing with their toys more”
“They want to interact with other dogs again”
“They are keen to go for longer walks”
“They used to be in pain, and now they are the pain”
“I have not seen them come up the stairs in years”
“They are not sleeping as much”
“They seem so much happier”
“They are not as anxious or grumpy”
“When can I get some of that?”
Things to keep in mind
Beransa is recommended for pets with joint pain associated with Osteoarthritis or degenerative joint disease. It may also be used for a short period to help reduce pain levels after joint injuries. The proven effectiveness has certainly given so many pets a new lease on life. That said, as with any medical treatment, whilst rare, there is always the potential for adverse reactions in a small percentage of patients. With over 25 Millions of doses used worldwide, it is also not uncommon for pets to have underlying health issues which may show symptoms whilst being treated with Beransa. Whilst these issues may not be directly linked to Beransa, to be overly cautious they need to be mentioned when reporting any potential side effects.
Medications like Beransa also need to be approved by governing and regulatory bodies such as the Australian Pesticide and Veterinary Medicine Authority, which helps unsure the safety and effectiveness.
For pets suffering from chronic or severe Osteoarthritic pain management treatments like Beransa can be life changing, however we do always need to ensure the utmost safety and take into account the risk benefit. It is also important to discuss and or diagnose any other health concerns prior to starting Beransa.
If you pet is starting on Beransa then here are some things to watch out for
- Swelling or pain at the injection site
- Inappetence
- Loose Motions / vomiting
- Increased drinking and urination
- Lethargy
- Tremors/drooling
Considering that Beransa ( Betinvetmab) is a protein, it will be broken down into natural amino acids and excreted from the body over 3-4 weeks. Any side effects should resolve once this has occurred.
Should your pet experience any issues after starting treatment it is important that you let us know.
